What is the 2021 Race-Free CKD-EPI Equation?
The 2021 CKD-EPI Creatinine equation estimates the glomerular filtration rate (eGFR) using serum creatinine, age, and sex. Unlike earlier formulas, it removes the race-based correction factor that historically adjusted results for Black patients. Eliminating that modifier promotes more equitable kidney care by ensuring every patient is assessed with the same standard. When a serum Cystatin C value is also available, the combined Creatinine–Cystatin C equation can provide a more precise estimate, since Cystatin C is less influenced by muscle mass and diet.